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Friday, April 27, 2007

A drug initially hailed by doctors as giving new hope to people who are at risk of diabetes should not be prescribed to them after all

Changes in lifestyle hold key to reducing risk of diabetes - Independent

This article contains such a lot of sense that ~I have quoted extensively from it. - It is rare to read such good sense on the subject of prescription drugs.

Extracts:

"A drug initially hailed by doctors as giving new hope to people who are at risk of diabetes should not be prescribed to them after all, experts will say today.

The drug, rosiglitazone, sharply reduces the chance of developing diabetes when given to people at high risk, according to the results of an international trial published last year.

But three American professors writing in the British Medical Journal say taking a prescription drug to prevent the condition cannot be justified when lifestyle changes can achieve the same effect.

Professor Victor Montori of the Mayo Clinic in Rochester, New York, and colleagues say the "aggressive marketing of rosiglitazone as a preventive therapy" following last year's trial is an example of how healthy people are being turned into patients through the medicalisation of everyday life.

Multinational pharmaceutical companies with an interest in promoting new drugs are increasingly identifying "pre-disease states" which require treatment before people fall ill, they say."

"Speaking yesterday, Professor Montori said: "Our main concern is the idea that you can turn people into patients very early by getting them to take pills. Diabetes is not a disease you feel you have, it is a disease your doctor tells you that you have. All the drugs do is prevent your blood sugar rising to a level that triggers the diagnosis."

"You end up with patients taking more drugs who are then at risk of getting side effects and who have to go for more check-ups. You have become a patient where previously you were at risk of becoming one."

Heart disease, obesity, high cholesterol and high blood pressure were other conditions where drugs were prescribed instead of lifestyle changes."

""There is a tendency then to identify obesity as a condition that needs treating and if you keep going you get to a point where being alive and eating is a risk factor. We should be very cautious about the medicalisation of people who feel healthy and then through treatment become patients."

"Rosiglitazone, marketed in the UK as Avandia by Glaxosmithkline, is an established treatment for people with diabetes, but last year's trial, run in 21 countries and published in The Lancet in September, was aimed at establishing its role in preventing the condition. The results showed that for every 1,000 people at high risk treated with the drug for three years, it would protect 144 who would otherwise have developed the condition.

But most of these people would be unaware of their condition, would not experience any immediate benefit, would require more visits to the doctor, and would have their anxiety levels raised by the diagnosis.

The authors say in the BMJ: "Even under the most optimistic assumptions, patients offered rosiglitazone for prevention will end up taking more pills. Thus neither patients who value preventing diabetes in order to avoid taking drugs, nor a society concerned with cost minimisation, will benefit from early use of rosiglitazone.""

To reduce the risk of developing type 2 diabetes, obesity, heart disease, high blood pressure and high cholesterol problems completely safely, all you need to do is stop eating salt and salty food, and do your damnedest to avoid taking prescribed drugs unless they are strictly necessary. - See http://www.wildeaboutsteroids.co.uk/conditions.html and http://www.wildeaboutsteroids.co.uk/steroids.html

Lose weight by eating less salt! Go on! - Try it! - You will feel so much better!
See my website www.wildeaboutsteroids.co.uk
(The site does not sell anything and has no banners or sponsors or adverts - just helpful information.)