BBC News reports that the "number of people in England having a limb amputated because of type-two diabetes has risen dramatically." Obviously this is related to the continuing rise in the number of people developing type 2 diabetes and also with the illness developing when people are younger than previously.
Type 2 diabetes occurs mostly in people who are overweight/obese, and it is one of the very serious side-effects of the many prescription drugs, e.g. corticosteroids, that weaken blood vessel walls, resulting in fluid retention/sodium retention/obesity/raised blood pressure and many other health problems.
To lower your risk of developing obesity, type 2 diabetes, etc. in the first place, it would be prudent to avoid prescription drugs unless they are really necessary, and make a serious effort to minimise your intake of salt/sodium and salty food. - Avoiding salty food entails avoiding the highly-salted processed foods like bacon, sausages, bread, cheese, cornflakes etc. See Sodium in foods
Read my Mensa article on Obesity and the Salt Connection
See advice for pregnant mothers
Children and Obesity