You are wondering whether you would lose weight if you cut down on or give up the amitriptyline you take? - Well the answer is that if you have gained weight as a side-effect of taking amitriptyline, you will almost certainly lose weight when you cut it down or gradually give it up. - But depending on how long you have been taking it and how high the dose, you may not be able to lose all the weight gained. - On the other hand, if you seriously reduce your intake of salt and salty food, it is actually possible to return to your previous weight or even lower! - Read about how amitriptyline causes weight gain, and about how to lose weight by eating less salt/sodium.